Peripheral Neuropathy Peripheral neuropathy is a nerve disorder. It may cause numbness, tingling, and weakness. It can also cause pain. These symptoms usually start in the longest nerves in the body and so first affect the feet and later the hands. This is sometimes called the stocking-glove pattern. The symptoms usually spread slowly and evenly up the legs and arms. Other body parts might also be affected. Most people who develop peripheral neuropathy are over age 55. But people can be affected at any age. . @dr_advaitkulkarni