Dr. Advait Kulkarni (Neurologist in Bengaluru) Myelin oligodendrocyte glycoprotein antibody disease (MOGAD) is a condition that causes inflammation in the nervous system. In MOGAD, antibodies attack a protein called myelin oligodendrocyte glycoprotein (MOG) Patients with persistently positive antibodies to MOG are at risk for recurrent events. Signs & amp; Symptoms MOG antibody disease preferentially causes inflammation in the optic nerve, but can also cause inflammation in the spinal cord, brain, and brainstem. Symptoms can include: • Loss or blurring of vision in one or both eyes • Loss of color vision • Paralysis (no motor function) of a limb or limbs • Paraparesis (weakness) of a limb or limbs • Loss of sensation • Loss of bladder or bowel control