Dr. Advait Kulkarni (Neurologist in Bengaluru) Treatment Neuromyelitis optica patients, with right management, can have long-term remission. NMO treatment involves therapies to reverse recent symptoms and prevent future attacks. • Reversing recent symptoms. In the early stage of an NMO attack, a steroid medication is given. That is given for about five days and then tapered off slowly. Plasma exchange is frequently recommended as the first or second treatment, usually in addition to steroid therapy. In this procedure, damaging antibodies are removed from your blood. Doctors can also help manage other possible symptoms, such as pain or muscle problems. • Preventing future attacks. Doctors might recommend that you take a lower dose of medications to prevent future NMO attacks and relapses.