Dr Advait Kulkarni (Neurologist at Bengaluru) Guillain-Barre syndrome is a rare disorder in which your body's immune system attacks your nerves. Weakness and tingling in your extremities are usually the first symptoms. These sensations can quickly spread, eventually paralyzing your whole body. Signs and symptoms of Guillain-Barre syndrome may include: • Prickling, pins and needles sensations in your fingers, toes, ankles or wrists • Weakness in your legs that spreads to your upper body • Unsteady walking or inability to walk or climb stairs • Difficulty with facial movements, including speaking, chewing or swallowing • Double vision or inability to move eyes • Severe pain that may feel achy, shooting or cramp like and may be worse at night • Difficulty with bladder control or bowel function • Rapid heart rate • Low or high blood pressure • Difficulty breathing